Guinea Pig Cytomegalovirus Protective T Cell Antigen GP83 Is a Functional pp65 Homolog for Innate Immune Evasion and Pentamer-Dependent Virus Tropism

The guinea pig is the only small animal model for congenital cytomegalovirus (CMV) but requires species-specific guinea pig cytomegalovirus (GPCMV). Tegument protein GP83 is the presumed homolog of HCMV pp65, but gene duplication in the UL82-UL84 homolog locus in various animal CMVs made it unclear...

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Vydáno v:J Virol
Hlavní autoři: Choi, K. Yeon, El-Hamdi, Nadia, Hornig, Julia, McGregor, Alistair
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139670/
https://ncbi.nlm.nih.gov/pubmed/33658350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00324-21
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