An Attenuated CMV Vaccine with a Deletion in Tegument Protein GP83 (pp65 Homolog) Protects against Placental Infection and Improves Pregnancy Outcome in a Guinea Pig Challenge Model

AIMS: Congenital human cytomegalovirus (HCMV) infection can lead to long-term neurodevelopmental sequelae, including mental retardation and sensorineural hearing loss. Preconception vaccine strategies relevant to prevention of HCMV-mediated injury to the newborn can be studied in the guinea pig cyto...

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Hlavní autoři: Schleiss, Mark R., Buus, Ryan, Choi, K. Yeon, McGregor, Alistair
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900008/
https://ncbi.nlm.nih.gov/pubmed/24465269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.13.107
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