An Endoplasmic Reticulum-Targeting Signal Sequence Enhances the Immunogenicity of an Immunorecessive Simian Virus 40 Large T Antigen Cytotoxic T-Lymphocyte Epitope

An immunological hierarchy among three H-2D(b)-restricted cytotoxic T lymphocyte (CTL) determinants in simian virus 40 (SV40) large T antigen (Tag) was described previously: determinants I and II/III are immunodominant, whereas determinant V is immunorecessive. To assess the immunogenicity of each d...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Fu, Tong-Ming, Mylin, Lawrence M., Schell, Todd D., Bacik, Igor, Russ, Gustav, Yewdell, Jonathan W., Bennink, Jack R., Tevethia, Satvir S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Viral Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1469-1481.1998
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