A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5

Human immunodeficiency virus type 1 (HIV-1) requires the presence of specific chemokine receptors in addition to CD4 to enter target cells. The chemokine receptor CCR5 is used by the macrophage-tropic strains of HIV-1 that predominate during the asymptomatic stages of infection. Here we identify a s...

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Main Authors: Farzan, Michael, Choe, Hyeryun, Vaca, Luis, Martin, Kathleen, Sun, Ying, Desjardins, Elizabeth, Ruffing, Nancy, Wu, Lijun, Wyatt, Richard, Gerard, Norma, Gerard, Craig, Sodroski, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124591/
https://ncbi.nlm.nih.gov/pubmed/9445013
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