Induction of Neutralizing Antibodies to T-Cell Line-Adapted and Primary Human Immunodeficiency Virus Type 1 Isolates with a Prime-Boost Vaccine Regimen in Chimpanzees

Five chimpanzees were immunized by administration of one or more intranasal priming doses of one to three recombinant adenoviruses containing a gp160 insert from human immunodeficiency virus type 1 (HIV-1) MN (HIV-1(MN)) followed by one or more boosts of recombinant HIV-1(SF2) gp120 delivered intram...

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Hlavní autoři: Zolla-Pazner, Susan, Lubeck, Michael, Xu, Serena, Burda, Sherri, Natuk, Robert J., Sinangil, Faruk, Steimer, Kathelyn, Gallo, Robert C., Eichberg, Jorg W., Matthews, Thomas, Robert-Guroff, Marjorie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Viral Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124577/
https://ncbi.nlm.nih.gov/pubmed/9444999
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