Induction of Neutralizing Antibodies to T-Cell Line-Adapted and Primary Human Immunodeficiency Virus Type 1 Isolates with a Prime-Boost Vaccine Regimen in Chimpanzees

Five chimpanzees were immunized by administration of one or more intranasal priming doses of one to three recombinant adenoviruses containing a gp160 insert from human immunodeficiency virus type 1 (HIV-1) MN (HIV-1(MN)) followed by one or more boosts of recombinant HIV-1(SF2) gp120 delivered intram...

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Pubblicato in:	J Virol
Autori principali:	Zolla-Pazner, Susan, Lubeck, Michael, Xu, Serena, Burda, Sherri, Natuk, Robert J., Sinangil, Faruk, Steimer, Kathelyn, Gallo, Robert C., Eichberg, Jorg W., Matthews, Thomas, Robert-Guroff, Marjorie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9444999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1052-1059.1998
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