Attenuation of the Vaccine Oka Strain of Varicella-Zoster Virus and Role of Glycoprotein C in Alphaherpesvirus Virulence Demonstrated in the SCID-hu Mouse

The SCID-hu mouse implanted with human fetal tissue is a novel model for investigating human viral pathogenesis. Infection of human skin implants was used to investigate the basis for the clinical attenuation of the varicella-zoster virus (VZV) strain, V-Oka, from which the newly licensed vaccine is...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moffat, Jennifer F., Zerboni, Leigh, Kinchington, Paul R., Grose, Charles, Kaneshima, Hideto, Arvin, Ann M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9444989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.965-974.1998
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