Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure

Atrial natriuretic peptide (ANP) is an important regulator of arterial blood pressure. The mechanisms mediating its hypotensive effects are complex and involve the inhibition of the sympathetic and renin-angiotensin-aldosterone (RAA) systems, increased diuresis/natriuresis, vasodilation, and enhance...

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Bibliographic Details
Main Authors: Holtwick, Rita, Gotthardt, Michael, Skryabin, Boris, Steinmetz, Martin, Potthast, Regine, Zetsche, Bernd, Hammer, Robert E., Herz, Joachim, Kuhn, Michaela
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124542/
https://ncbi.nlm.nih.gov/pubmed/11997476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102650499
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