Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function

The cardiac natriuretic peptides (NPs), atrial NP and B-type NP, regulate fluid homeostasis and arterial BP through renal actions involving increased GFR and vascular and tubular effects. Guanylyl cyclase-A (GC-A), the transmembrane cGMP-producing receptor shared by these peptides, is expressed in d...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Staffel, Janina, Valletta, Daniela, Federlein, Anna, Ehm, Katharina, Volkmann, Regine, Füchsl, Andrea M., Witzgall, Ralph, Kuhn, Michaela, Schweda, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198264/
https://ncbi.nlm.nih.gov/pubmed/27153922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070731
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