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Positive selection of self-MHC-reactive T cells by individual peptide–MHC class II complexes

If T cells require specific interactions with MHC-bound peptides during positive selection, then the specificities of T cells selected by one peptide should be distinct from those selected by another. We have examined positive selection of CD4 T cells in four strains of mice, each overexpressing a d...

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Bibliografski detalji
Glavni autori: Barton, Gregory M., Beers, Courtney, deRoos, Paul, Eastman, Susan R., Gomez, Marcela E., Forbush, Katherine A., Rudensky, Alexander Y.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124507/
https://ncbi.nlm.nih.gov/pubmed/12011451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102645699
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