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Invariant Chain–independent Function of H-2M in the Formation of Endogenous Peptide–Major Histocompatibility Complex Class II Complexes In Vivo

Efficient loading of major histocompatibility complex class II molecules with peptides requires the invariant chain (Ii) and the class II–like molecule H-2M. Recent in vitro biochemical studies suggest that H2-M may function as a chaperone to rescue empty class II dimers. To test this hypothesis in...

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Dettagli Bibliografici
Autori principali: Kovats, Susan, Grubin, Catherine E., Eastman, Susan, deRoos, Paul, Dongre, Ashok, Kaer, Luc Van, Rudensky, Alexander Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212101/
https://ncbi.nlm.nih.gov/pubmed/9432982
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