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Invariant Chain–independent Function of H-2M in the Formation of Endogenous Peptide–Major Histocompatibility Complex Class II Complexes In Vivo

Efficient loading of major histocompatibility complex class II molecules with peptides requires the invariant chain (Ii) and the class II–like molecule H-2M. Recent in vitro biochemical studies suggest that H2-M may function as a chaperone to rescue empty class II dimers. To test this hypothesis in...

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Autors principals: Kovats, Susan, Grubin, Catherine E., Eastman, Susan, deRoos, Paul, Dongre, Ashok, Kaer, Luc Van, Rudensky, Alexander Y.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212101/
https://ncbi.nlm.nih.gov/pubmed/9432982
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