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Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages

Cathepsin S (catS) and cathepsin L (catL) mediate late stages of invariant chain (Ii) degradation in discrete antigen-presenting cell types. Macrophages (Mφs) are unique in that they express both proteases and here we sought to determine the relative contribution of each enzyme. We observe that catL...

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Detalhes bibliográficos
Main Authors: Beers, Courtney, Honey, Karen, Fink, Susan, Forbush, Katherine, Rudensky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193812/
https://ncbi.nlm.nih.gov/pubmed/12538657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020978
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