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Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform

PAX6 is an evolutionarily conserved transcription factor that plays a critical role in vertebrate and invertebrate eye formation. Heterozygous null mutations in the PAX6 gene result in aniridia in humans and a distinct small eye syndrome in rodents. Vertebrates primarily express two alternatively sp...

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Detaylı Bibliyografya
Asıl Yazarlar: Singh, Sanjaya, Mishra, Rajnikant, Arango, Nelson A., Deng, Jian Min, Behringer, Richard R., Saunders, Grady F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC124485/
https://ncbi.nlm.nih.gov/pubmed/11983873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102691299
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