Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform
PAX6 is an evolutionarily conserved transcription factor that plays a critical role in vertebrate and invertebrate eye formation. Heterozygous null mutations in the PAX6 gene result in aniridia in humans and a distinct small eye syndrome in rodents. Vertebrates primarily express two alternatively sp...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102691299 |
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