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C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.

Pax-5 encodes the transcription factor BSAP which plays an essential role in early B cell development and midbrain patterning. In this study we have analysed the structural requirements for transcriptional activation by BSAP. In vitro mutagenesis and transient transfection experiments indicate that...

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Publicat a:EMBO J
Autors principals: Dörfler, P, Busslinger, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617244/
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