Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform

PAX6 is an evolutionarily conserved transcription factor that plays a critical role in vertebrate and invertebrate eye formation. Heterozygous null mutations in the PAX6 gene result in aniridia in humans and a distinct small eye syndrome in rodents. Vertebrates primarily express two alternatively sp...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Singh, Sanjaya, Mishra, Rajnikant, Arango, Nelson A., Deng, Jian Min, Behringer, Richard R., Saunders, Grady F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102691299
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