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Cocaine sensitization and reward are under the influence of circadian genes and rhythm

Investigations using the fruit fly Drosophila melanogaster have shown that the circadian clock gene period (Per) can influence behavioral responses to cocaine. Here we show that the mouse homologues of the Drosophila Per gene, mPer1 and mPer2, modulate cocaine sensitization and reward, two phenomena...

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Bibliografske podrobnosti
Main Authors: Abarca, Carolina, Albrecht, Urs, Spanagel, Rainer
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC124417/
https://ncbi.nlm.nih.gov/pubmed/12084940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142039099
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