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Cocaine sensitization and reward are under the influence of circadian genes and rhythm

Investigations using the fruit fly Drosophila melanogaster have shown that the circadian clock gene period (Per) can influence behavioral responses to cocaine. Here we show that the mouse homologues of the Drosophila Per gene, mPer1 and mPer2, modulate cocaine sensitization and reward, two phenomena...

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Detalhes bibliográficos
Main Authors: Abarca, Carolina, Albrecht, Urs, Spanagel, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124417/
https://ncbi.nlm.nih.gov/pubmed/12084940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142039099
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