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Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells
Gene amplification is a common form of genomic instability in a wide variety of organisms and is often associated with tumor progression in mammals. One striking feature of many amplified genes is their organization as large inverted duplications (palindromes). Here, we describe a molecular mechanis...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124374/ https://ncbi.nlm.nih.gov/pubmed/12060719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132275999 |
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