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Hidden Markov models from molecular dynamics simulations on DNA

An enhanced bioinformatics tool incorporating the participation of molecular structure as well as sequence in protein DNA recognition is proposed and tested. Boltzmann probability models of sequence-dependent DNA structure from all-atom molecular dynamics simulations were obtained and incorporated i...

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Autors principals: Thayer, Kelly M., Beveridge, D. L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124344/
https://ncbi.nlm.nih.gov/pubmed/12072566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132148699
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