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Hidden Markov models from molecular dynamics simulations on DNA
An enhanced bioinformatics tool incorporating the participation of molecular structure as well as sequence in protein DNA recognition is proposed and tested. Boltzmann probability models of sequence-dependent DNA structure from all-atom molecular dynamics simulations were obtained and incorporated i...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124344/ https://ncbi.nlm.nih.gov/pubmed/12072566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132148699 |
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