Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-α responses

Lipopolysaccharide (LPS) stimulation of the innate immune response requires the activation of signaling cascades that culminate in the synthesis and secretion of proinflammatory cytokines. Given the inhibitory effects of phosphodiesterase (PDE) inhibitors on LPS-induced cytokine production, we have...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Jin, S.-L. Catherine, Conti, Marco
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 2002
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.122041599
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