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Evaluating conformational free energies: The colony energy and its application to the problem of loop prediction

In this paper, we introduce a method to account for the shape of the potential energy curve in the evaluation of conformational free energies. The method is based on a procedure that generates a set of conformations, each with its own force-field energy, but adds a term to this energy that favors co...

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Detalhes bibliográficos
Main Authors: Xiang, Zhexin, Soto, Cinque S., Honig, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124248/
https://ncbi.nlm.nih.gov/pubmed/12032300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102179699
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