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Use of gene expression profiling to direct in vivo molecular imaging of lung cancer
Using gene expression profiling, we identified cathepsin cysteine proteases as highly up-regulated genes in a mouse model of human lung adenocarcinoma. Overexpression of cathepsin proteases in these lung tumors was confirmed by immunohistochemistry and Western blotting. Therefore, an optical probe a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242291/ https://ncbi.nlm.nih.gov/pubmed/16183744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503920102 |
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