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Imaging Primary Lung Cancers in Mice to Study Radiation Biology

PURPOSE: To image a genetically engineered mouse model of non-small cell lung cancer with micro-CT to measure tumor response to radiation therapy. METHODS AND MATERIALS: The Cre-loxP system was utilized to generate primary lung cancers in mice with mutation in K-ras alone or in combination with p53...

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Detalhes bibliográficos
Main Authors: Kirsch, David G., Grimm, Jan, Guimaraes, Alexander R., Wojtkiewicz, Gregory R., Perez, Bradford A., Santiago, Philip M., Anthony, Nikolas K., Forbes, Thomas, Doppke, Karen, Weissleder, Ralph, Jacks, Tyler
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847457/
https://ncbi.nlm.nih.gov/pubmed/20206017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.11.038
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