Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway

The transmembrane protein Notch is cleaved by γ-secretase to yield an active form, Notch intracellular domain (Notch-IC), in response to the binding of ligands, such as Jagged. Notch-IC contributes to the regulation of a variety of cellular events, including cell fate determination during embryonic...

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Autori principali: Kim, Jin Woo, Kim, Myung Jin, Kim, Kwang Je, Yun, Hee Jae, Chae, Ji Soo, Hwang, Sang Gil, Chang, Tong-Shin, Park, Hee-Sae, Lee, Kang-Woo, Han, Pyung-Lim, Cho, Ssang-Goo, Kim, Tae-Wan, Choi, Eui-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242280/
https://ncbi.nlm.nih.gov/pubmed/16179393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501600102
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