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Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway
The transmembrane protein Notch is cleaved by γ-secretase to yield an active form, Notch intracellular domain (Notch-IC), in response to the binding of ligands, such as Jagged. Notch-IC contributes to the regulation of a variety of cellular events, including cell fate determination during embryonic...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242280/ https://ncbi.nlm.nih.gov/pubmed/16179393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501600102 |
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