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A plausible model for the digital response of p53 to DNA damage
Recent observations show that the single-cell response of p53 to ionizing radiation (IR) is “digital” in that it is the number of oscillations rather than the amplitude of p53 that shows dependence on the radiation dose. We present a model of this phenomenon. In our model, double-strand break (DSB)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242279/ https://ncbi.nlm.nih.gov/pubmed/16186499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501352102 |
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