An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae.

Chlorpyrifos targets mammalian brain development through a combination of effects directed at cholinergic receptors and intracellular signaling cascades that are involved in cell differentiation. We used sea urchin embryos as an invertebrate model system to explore the cellular mechanisms underlying...

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Hlavní autoři: Buznikov, G A, Nikitina, L A, Bezuglov, V V, Lauder, J M, Padilla, S, Slotkin, T A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240367/
https://ncbi.nlm.nih.gov/pubmed/11485862
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