The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity.

Embryonic development in the sea urchin requires trophic actions of the same neurotransmitters that participate in mammalian brain assembly. We evaluated the development of the high-affinity choline transporter, which controls acetylcholine synthesis. A variety of developmental neurotoxicants affect...

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Hauptverfasser: Qiao, Dan, Nikitina, Lyudmila A, Buznikov, Gennady A, Lauder, Jean M, Seidler, Frederic J, Slotkin, Theodore A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241715/
https://ncbi.nlm.nih.gov/pubmed/14594623
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