Vaccination with Recombinant Aspartic Hemoglobinase Reduces Parasite Load and Blood Loss after Hookworm Infection in Dogs

BACKGROUND: Hookworms infect 730 million people in developing countries where they are a leading cause of intestinal blood loss and iron-deficiency anemia. At the site of attachment to the host, adult hookworms ingest blood and lyse the erythrocytes to release hemoglobin. The parasites subsequently...

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Main Authors: Loukas, Alex, Bethony, Jeffrey M, Mendez, Susana, Fujiwara, Ricardo T, Goud, Gaddam Narsa, Ranjit, Najju, Zhan, Bin, Jones, Karen, Bottazzi, Maria Elena, Hotez, Peter J
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2005
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240050/
https://ncbi.nlm.nih.gov/pubmed/16231975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020295
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