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Dual roles for cholesterol in mammalian cells

The structural features of sterols required to support mammalian cell growth have not been fully defined. Here, we use mutant CHO cells that synthesize only small amounts of cholesterol to test the capacity of various sterols to support growth. Sterols with minor modifications of the side chain (e.g...

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Detalhes bibliográficos
Main Authors: Xu, Fang, Rychnovsky, Scott D., Belani, Jitendra D., Hobbs, Helen H., Cohen, Jonathan C., Rawson, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1239893/
https://ncbi.nlm.nih.gov/pubmed/16199524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503590102
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