Streptomyces Serine Protease (DHP-A) as a New Biocatalyst Capable of Forming Chiral Intermediates of 1,4-Dihydropyridine Calcium Antagonists

Streptomyces viridosporus A-914 was screened as a producer of an enzyme to effectively form chiral intermediates of 1,4-dihydropyridine calcium antagonists. The supernatant liquid of the growing culture of this strain exhibited high activity for enantioselective hydrolysis of prochiral 1,4-dihydropy...

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Pubblicato in:	Appl Environ Microbiol
Autori principali:	Arisawa, Akira, Matsufuji, Motoko, Nakashima, Takashi, Dobashi, Kazuyuki, Isshiki, Kunio, Yoshioka, Takeo, Yamada, Shigeru, Momose, Haruo, Taguchi, Seiichi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Enzymology and Protein Engineering
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12039725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.68.6.2716-2725.2002
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