Streptomyces Serine Protease (DHP-A) as a New Biocatalyst Capable of Forming Chiral Intermediates of 1,4-Dihydropyridine Calcium Antagonists

Streptomyces viridosporus A-914 was screened as a producer of an enzyme to effectively form chiral intermediates of 1,4-dihydropyridine calcium antagonists. The supernatant liquid of the growing culture of this strain exhibited high activity for enantioselective hydrolysis of prochiral 1,4-dihydropy...

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Detalhes bibliográficos
Main Authors: Arisawa, Akira, Matsufuji, Motoko, Nakashima, Takashi, Dobashi, Kazuyuki, Isshiki, Kunio, Yoshioka, Takeo, Yamada, Shigeru, Momose, Haruo, Taguchi, Seiichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Enzymology and Protein Engineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123970/
https://ncbi.nlm.nih.gov/pubmed/12039725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.6.2716-2725.2002
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