Bacteriophage Resistance of a ΔthyA Mutant of Lactococcus lactis Blocked in DNA Replication

The thyA gene, which encodes thymidylate synthase (TS), of Lactococcus lactis CHCC373 was sequenced, including the upstream and downstream regions. We then deleted part of thyA by gene replacement. The resulting strain, MBP71 ΔthyA, was devoid of TS activity, and in media without thymidine, such as...

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書誌詳細

出版年:	Appl Environ Microbiol
主要な著者:	Pedersen, Martin B., Jensen, Peter R., Janzen, Thomas, Nilsson, Dan
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Physiology and Biotechnology
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12039762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.68.6.3010-3023.2002
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