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Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Activated phagocytes release the haem enzyme MPO (myeloperoxidase) and produce superoxide radicals and H(2)O(2) via an oxidative burst. MPO uses H(2)O(2) and Cl(−) to form HOCl, the physiological mixture of hypochlorous acid and its anion present at pH 7.4. As MPO binds to glycosaminoglycans, oxidat...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Portland Press Ltd.
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237146/ https://ncbi.nlm.nih.gov/pubmed/15932347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050630 |
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