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Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Activated phagocytes release the haem enzyme MPO (myeloperoxidase) and also generate superoxide radicals (O(2)(•−)), and hence H(2)O(2), via an oxidative burst. Reaction of MPO with H(2)O(2) in the presence of chloride ions generates HOCl (the physiological mixture of hypochlorous acid and its anion...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Portland Press Ltd.
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133775/ https://ncbi.nlm.nih.gov/pubmed/15078224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040148 |
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