Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools

We have shown previously that LPPs (lipid phosphate phosphatases) reduce the stimulation of the p42/p44 MAPK (p42/p44 mitogen-activated protein kinase) pathway by the GPCR (G-protein-coupled receptor) agonists S1P (sphingosine 1-phosphate) and LPA (lysophosphatidic acid) in serum-deprived HEK-293 ce...

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Autores principales: Long, Jaclyn, Darroch, Peter, Wan, Kah Fei, Kong, Kok Choi, Ktistakis, Nicholas, Pyne, Nigel J., Pyne, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2005
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237135/
https://ncbi.nlm.nih.gov/pubmed/15960610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050342
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