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mRNA with a <20-nt poly(A) tail imparted by the poly(A)-limiting element is translated as efficiently in vivo as long poly(A) mRNA

The poly(A)-limiting element (PLE) is a conserved sequence that restricts the length of the poly(A) tail to <20 nt. This study compared the translation of PLE-containing short poly(A) mRNA expressed in cells with translation in vitro of mRNAs with varying length poly(A) tails. In transfected cell...

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Hlavní autoři: PENG, JING, SCHOENBERG, DANIEL R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by RNA Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237109/
https://ncbi.nlm.nih.gov/pubmed/15929942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2470905
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