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Translation of poly(A) tails leads to precise mRNA cleavage

Translation of poly(A) tails leads to mRNA cleavage but the mechanism and global pervasiveness of this “nonstop/no-go” decay process is not understood. Here we performed ribosome profiling (in a yeast strain lacking exosome function) of short 15–18 nucleotides mRNA footprints to identify ribosomes s...

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Bibliographic Details
Published in:RNA
Main Authors: Guydosh, Nicholas R., Green, Rachel
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393183/
https://ncbi.nlm.nih.gov/pubmed/28193672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060418.116
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