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Nuclear Aggresomes Form by Fusion of PML-associated Aggregates

Nuclear aggregates formed by proteins containing expanded poly-glutamine (poly-Q) tracts have been linked to the pathogenesis of poly-Q neurodegenerative diseases. Here, we show that a protein (GFP170(*)) lacking poly-Q tracts forms nuclear aggregates that share characteristics of poly-Q aggregates....

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Detalhes bibliográficos
Main Authors: Fu, Lianwu, Gao, Ya-sheng, Tousson, Albert, Shah, Anish, Chen, Tung-Ling L., Vertel, Barbara M., Sztul, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237092/
https://ncbi.nlm.nih.gov/pubmed/16055507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-01-0019
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