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Interleukin-12 Receptor β1 or Interleukin-12 Receptor β2 deficiency in mice indicates that Interleukin-12 and Interleukin-23 are not essential for host recovery from viral encephalitis.

Vesicular Stomatitis Virus (VSV), a negative sense, single-stranded RNA Rhabdovirus causes acute viral encephalitis when administered intranasally to mice. Interleukin-12 (IL-12) is a key pro-inflammatory cytokine, produced largely by the antigen presenting cells (APC) that bridges the innate and ac...

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Detalhes bibliográficos
Main Authors: Ireland, Derek D.C., Palian, Beth M., Reiss, Carol Shoshkes
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237019/
https://ncbi.nlm.nih.gov/pubmed/16035952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2005.18.397
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