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Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases
The interleukin (IL)-12–type cytokines IL-12 and IL-23 are involved in T-helper (Th) 1 and Th17 immunity, respectively. They share the IL-12 receptor β1 (IL-12Rβ1) as one component of their receptor signaling complexes, with IL-12Rβ2 as second receptor for IL-12 and IL-23R for IL-23 signal transduct...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945146/ https://ncbi.nlm.nih.gov/pubmed/27193299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-12-1645 |
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