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Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough
The Upf proteins are essential for nonsense-mediated mRNA decay (NMD). They have also been implicated in the modulation of translational fidelity at viral frameshift signals and premature termination codons. How these factors function in both mRNA turnover and translational control remains unclear....
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Formato: | Artigo |
Idioma: | Inglês |
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Copyright 2004 by RNA Society
2004
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1236997/ https://ncbi.nlm.nih.gov/pubmed/15388879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7120504 |
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