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Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough

The Upf proteins are essential for nonsense-mediated mRNA decay (NMD). They have also been implicated in the modulation of translational fidelity at viral frameshift signals and premature termination codons. How these factors function in both mRNA turnover and translational control remains unclear....

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Detalhes bibliográficos
Main Authors: HARGER, JASON W., DINMAN, JONATHAN D.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236997/
https://ncbi.nlm.nih.gov/pubmed/15388879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7120504
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