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The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells
Transcription factors NF-κB1 and c-Rel, individually dispensable during embryogenesis, serve similar, yet distinct, roles in the function of mature hemopoietic cells. Redundancy among Rel/NF-κB family members prompted an examination of the combined roles of c-Rel and NF-κB1 by using mice that lack b...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123679/ https://ncbi.nlm.nih.gov/pubmed/11930006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072071599 |
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