The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27(kip1)) expression

MLL, involved in many chromosomal translocations associated with acute myeloid and lymphoid leukemia, has >50 known partner genes with which it is able to form in-frame fusions. Characterizing important downstream target genes of MLL and of MLL fusion proteins may provide rational therapeutic str...

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Detaylı Bibliyografya
Asıl Yazarlar: Xia, Zhen-Biao, Popovic, Relja, Chen, Jing, Theisler, Catherine, Stuart, Tara, Santillan, Donna A., Erfurth, Frank, Diaz, Manuel O., Zeleznik-Le, Nancy J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236570/
https://ncbi.nlm.nih.gov/pubmed/16169901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506464102
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