Low TRBP Levels Support an Innate Human Immunodeficiency Virus Type 1 Resistance in Astrocytes by Enhancing the PKR Antiviral Response

Acute human immunodeficiency virus type 1 (HIV-1) replication in astrocytes produces minimal new virus particles due, in part, to inefficient translation of viral structural proteins despite high levels of cytoplasmic viral mRNA. We found that a highly reactive double-stranded (ds) RNA-binding prote...

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Bibliografiske detaljer
Main Authors: Ong, Chi L., Thorpe, Janine C., Gorry, Paul R., Bannwarth, Sylvie, Jaworowski, Anthony, Howard, Jane L., Chung, Sean, Campbell, Shahan, Christensen, Helen S., Clerzius, Guerline, Mouland, Andrew J., Gatignol, Anne, Purcell, Damian F. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235869/
https://ncbi.nlm.nih.gov/pubmed/16188979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12763-12772.2005
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