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Low TRBP Levels Support an Innate Human Immunodeficiency Virus Type 1 Resistance in Astrocytes by Enhancing the PKR Antiviral Response

Acute human immunodeficiency virus type 1 (HIV-1) replication in astrocytes produces minimal new virus particles due, in part, to inefficient translation of viral structural proteins despite high levels of cytoplasmic viral mRNA. We found that a highly reactive double-stranded (ds) RNA-binding prote...

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Bibliographic Details
Main Authors: Ong, Chi L., Thorpe, Janine C., Gorry, Paul R., Bannwarth, Sylvie, Jaworowski, Anthony, Howard, Jane L., Chung, Sean, Campbell, Shahan, Christensen, Helen S., Clerzius, Guerline, Mouland, Andrew J., Gatignol, Anne, Purcell, Damian F. J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235869/
https://ncbi.nlm.nih.gov/pubmed/16188979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12763-12772.2005
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