Inhibition of Interferon-Stimulated JAK-STAT Signaling by a Tick-Borne Flavivirus and Identification of NS5 as an Interferon Antagonist

The tick-borne encephalitis (TBE) complex of viruses, genus Flavivirus, can cause severe encephalitis, meningitis, and/or hemorrhagic fevers. Effective interferon (IFN) responses are critical to recovery from infection with flaviviruses, and the mosquito-borne flaviviruses can inhibit this response....

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Detalhes bibliográficos
Main Authors: Best, Sonja M., Morris, Keely L., Shannon, Jeffrey G., Robertson, Shelly J., Mitzel, Dana N., Park, Gregory S., Boer, Elena, Wolfinbarger, James B., Bloom, Marshall E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235813/
https://ncbi.nlm.nih.gov/pubmed/16188985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12828-12839.2005
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