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Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
Tick-borne flaviviruses are maintained in nature in an enzootic cycle involving a tick vector and a vertebrate host. Thus, the virus replicates in two disparate hosts, each providing selective pressures that can influence virus replication and pathogenicity. To identify viral determinants associated...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592254/ https://ncbi.nlm.nih.gov/pubmed/18823640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.030 |
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