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Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity

Tick-borne flaviviruses are maintained in nature in an enzootic cycle involving a tick vector and a vertebrate host. Thus, the virus replicates in two disparate hosts, each providing selective pressures that can influence virus replication and pathogenicity. To identify viral determinants associated...

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Detalhes bibliográficos
Main Authors: Mitzel, Dana N., Best, Sonja M., Masnick, Max F., Porcella, Stephen F., Wolfinbarger, James B., Bloom, Marshall E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592254/
https://ncbi.nlm.nih.gov/pubmed/18823640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.030
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