Precise Estimation of Allele Frequencies of Single-Nucleotide Polymorphisms by a Quantitative SSCP Analysis of Pooled DNA

We show that single-nucleotide polymorphisms (SNPs) of moderate to high heterozygosity (minor allele frequencies >10%) can be efficiently detected, and their allele frequencies accurately estimated, by pooling the DNA samples and applying a capillary-based SSCP analysis. In this method, alleles a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sasaki, Tomonari, Tahira, Tomoko, Suzuki, Akari, Higasa, Koichiro, Kukita, Yoji, Baba, Shingo, Hayashi, Kenshi
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2001
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234915/
https://ncbi.nlm.nih.gov/pubmed/11083945
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky